FACTS ABOUT GR REVEALED

A single nucleotide polymorphism that replaces A with G in the nucleoside 3669 (A3669G) located in the 3’ end of exon 9b has become described in a ecu inhabitants (461). This polymorphism will not change the amino acid sequence but improves the steadiness of GRb mRNA and increases GRb protein expression, bringing about greater inhibition of GRa-i